Customization: | Available |
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CAS No.: | 53-84-9 |
Formula: | C21h26n7o14p2 |
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β-Nicotinamide adenine dinucleotide (β-NAD), a pyridine nucleotide and biologically active form of nicotinic acid, is a coenzyme necessary for the catalytic reaction of certain enzymes. β-NAD is a carrier for hydride ion, forming β-NADH. Hydride ion is enzymatically removed from a substrate molecule by the action of dehydrogenases such as malic dehydrogenase and lactic dehydrogenase. Such enzymes catalyze the reversible transfer of a hydride ion from malate or lactate to β-NAD to form the reduced product, β-NADH. Unlike β-NAD which has no absorbance at 340 nm, β-NADH absorbs at 340 nm (EmM = 6.22). The increase in absorbance at 340 nm with the formation of β-NADH is the basis for measurement of activity of many enzymes.
β-NAD is very hygroscopic and should be stored desiccated.Aqueous solutions between pH 2 - 6, stored as single-use aliquots at -70 °C, are stable for at least 6 months. Neutral or slightly acidic solutions are stable at 0 °C for at least 2 weeks. Solutions are rapidly degraded upon heating and are very labile in alkaline solutions, especially in the presence of phosphate, maleate, or carbonate. The rates of degradation of solutions at different pH and temperature conditions have been reported. Solutions are also sensitive to light.
Beta-NAD CAS: 53-84-9 | |
ITEMS | SPECIFICATION |
Appearance | White Powder |
Purity, % | ≥99% |
Moisture | <6% |
Solubilit | 200mg/ml |
Organic Solvent Residue | <4% |
β-Nicotinamide adenine dinucleotide has been used in the master mix of a coupled enzyme assay to estimate pectin methylesterase activity.
β-nicotinamide adenine dinucleotide (NAD +) and β-nicotinamide adenine dinucleotide reduced (NADH) contain coenzyme redox pairs (NAD+:NADH) involved in a wide range of enzyme-catalyzed redox reactions.
In addition to its redox function, NAD+/NADH is a donor of the ADP-ribose unit in ADP-ribosyltransferase (ADP-ribosyltransferase; poly(ADP-ribose) polymerase) reactions and a precursor of cyclic ADP-ribose (ADP-ribosyl cyclase).
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A: Well, it is widely used in medicine, nutrition, health food, dietary supplements, whitening products, cosmetics, etc.
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